Originally posted by Cyb3r
Not necessarily, only if the game devs made the eboots identical, you can compare them in HxD (drag and drop both eboots to HxD then press CTRL+K), if they are identical it will give you message saying "The chosen files are identical".
I don't have the exact BCUS debug eboot to check, but the regions share the same offsets I believe. I'm pretty sure that the debug works on either region. The regular eboot works on both just requires you to replace every time. Sounds like they are identical!